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Human insulin is a synthetic form of the natural hormone insulin, which is essential for regulating blood glucose levels in the body. It is primarily used in the treatment of diabetes mellitus, a condition where the body either does not produce enough insulin (Type 1 diabetes) or cannot use it effectively (Type 2 diabetes). Human insulin is produced using recombinant DNA technology, where the human insulin gene is inserted into bacteria (usually E. coli) or yeast cells to mass-produce the hormone in laboratories. This method results in insulin that is structurally identical to that produced by the human pancreas, offering improved compatibility and reduced allergic reactions compared to older animal-derived insulin.
There are several types of human insulin available, including short-acting (regular insulin) and intermediate-acting (NPH insulin), which differ in onset, peak time, and duration of action. These forms can be used alone or in combination depending on a patient’s needs and blood glucose control goals. Human insulin has largely been supplemented or replaced in some areas by insulin analogs, which offer more predictable absorption and action profiles. However, human insulin remains a critical and more affordable option in many regions, especially in low- and middle-income countries, and continues to play a central role in diabetes management worldwide.
Human insulin is a synthetic form of the natural hormone insulin, which is essential for regulating blood glucose levels in the body. It is primarily used in the treatment of diabetes mellitus, a condition where the body either does not produce enough insulin (Type 1 diabetes) or cannot use it effectively (Type 2 diabetes). Human insulin is produced using recombinant DNA technology, where the human insulin gene is inserted into bacteria (usually E. coli) or yeast cells to mass-produce the hormone in laboratories. This method results in insulin that is structurally identical to that produced by the human pancreas, offering improved compatibility and reduced allergic reactions compared to older animal-derived insulin.
There are several types of human insulin available, including short-acting (regular insulin) and intermediate-acting (NPH insulin), which differ in onset, peak time, and duration of action. These forms can be used alone or in combination depending on a patient’s needs and blood glucose control goals. Human insulin has largely been supplemented or replaced in some areas by insulin analogs, which offer more predictable absorption and action profiles. However, human insulin remains a critical and more affordable option in many regions, especially in low- and middle-income countries, and continues to play a central role in diabetes management worldwide.
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